VRTX - Vertex Pharmaceuticals - Stock Forecast

Healthcare - Sector
Coverage Profile Stock analysts Price Targets & Ratings Chart Insider Trading

VRTX is currently covered by 29 analysts with an average price target of $551.88. This is a potential upside of $52.14 (10.43%) from yesterday's end of day stock price of $499.74.

Vertex Pharmaceuticals's activity chart (see below) currently has 1,009 price targets and 753 ratings on display. The stock rating distribution of VRTX is 70.83% BUY, 27.78% HOLD and 1.39% SELL.

Stock Analyst Price Targets - Review

Analysts average stock forecasts to be materialized ratio is 77.05% with an average time for these price targets to be met of 197.45 days.

Highest price target for VRTX is $665, Lowest price target is $350, average price target is $551.88.

Most recent stock forecast was given by BRIAN ABRAHAMS from RBC on 08-Oct-2026. First documented stock forecast 15-Dec-2011.

What is Vertex Pharmaceuticals?

Vertex Pharmaceuticals is a biotechnology company that develops and commercializes therapies for treating cystic fibrosis (CF), a genetic disease that affects the lungs and digestive system. Vertex founded in 1989 at Boston, Massachusetts.

Products of Vertex Pharmaceuticals

TRIKAFTA/KAFTRIO and SYMDEKO/SYMKEVI

Regulators have approved these medications for the treatment of patients aged 6 years or older with at least one F508del mutation.

ORKAMBI

The FDA has approved this medication for treating CF homozygous F508del mutation patients aged 2 years or older.

KALYDECO

Which was approved by the U.S. Food and Drug Administration (FDA) in 2012. KALYDECO is a medication that is approved for treating CF patients who have a specific mutation that is responsive to ivacaftor.

In addition to these drugs, Vertex Pharmaceuticals has a pipeline of drugs in various stages of clinical development. VX-522, a CF mRNA therapeutic designed to treat the underlying cause of CF, is currently in Phase 1 clinical trials. VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain, is in Phase 3 clinical trials. The company is also developing Exa-cel for the treatment of sickle cell disease and transfusion-dependent beta-thalassemia, which is in Phase 2/3 clinical trials, and VX-864 for the treatment of alpha-1 antitrypsin (AAT) deficiency, which is in Phase 2 clinical trials. The company is also developing drugs to treat cancer and other genetic diseases.

Vertex Pharmaceuticals’ Performance History

The company had also entered into collaborations with several biotechnology firms, such as CRISPR Therapeutics, Moderna, Entrada Therapeutics, Affinia Therapeutics, Arbor Biotechnologies, Kymera Therapeutics, Mammoth Biosciences, Obsidian Therapeutics, Verve Therapeutics, Skyhawk Therapeutics, and Ribometrix.

Vertex Pharmaceuticals’ contribution to treating CF has been recognized through its products. The FDA approved TRIKAFTA/KAFTRIO in 2018, and it was later approved in Europe in 2019.

The drug demonstrated significant improvement in lung function and quality of life in CF patients.

Currently out of the existing stock ratings of VRTX, 51 are a BUY (70.83%), 20 are a HOLD (27.78%), 1 are a SELL (1.39%).

Split History since 2000:

8/24/00 2 for 1

Analyst name

Rating

Current price target

Potential Upside

Previous price target

Date of last PT

Price targets met ratio

Average potential upside

Average Days to Hit Target

Performance score

Buy Since 13-Feb-2026

$576

$76.26 (15.26%)

$570

11 days ago
(08-Oct-2026)

57/63 (90.48%)

$72.75 (14.46%)

151

Buy Since 07-Jan-2026

$615

$115.26 (23.06%)

$585

21 days ago
(28-Sep-2026)

33/35 (94.29%)

$87.33 (16.55%)

331

Buy Since 24-Oct-2022

$560

$60.26 (12.06%)

$530

1 months 8 days ago
(11-Sep-2026)

13/14 (92.86%)

$44.56 (8.65%)

133

Buy Since 05-Dec-2025

$665

$165.26 (33.07%)

$616

1 months 17 days ago
(02-Sep-2026)

10/15 (66.67%)

$108.25 (19.44%)

126

Buy Since 13-Jul-2026

$565

$65.26 (13.06%)

$560

2 months 14 days ago
(05-Aug-2026)

0/2 (0%)

$80.17 (16.54%)

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What is VRTX (Vertex Pharmaceuticals) average time for price targets to be met?

On average it took 197 days for the stock forecasts to be reached, with an average price target met ratio of 77.05%.

Which analyst most recently updated their price target on VRTX (Vertex Pharmaceuticals)?

Brian Abrahams

Which analyst has the most public recommendations on VRTX (Vertex Pharmaceuticals)?

Brian Abrahams works at RBC and has 42 price targets and 25 ratings on VRTX

Which analyst is the currently most bullish on VRTX (Vertex Pharmaceuticals)?

Terence Flynn with the highest potential upside of $165.26

Which analyst is the currently most reserved on VRTX (Vertex Pharmaceuticals)?

Matthew Roden with the lowest potential downside of -$339.74
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